How Daytrana® works

Because Daytrana is a patch, it delivers medicine in a different way to treat the symptoms of ADHD.

The Daytrana® patch is a transdermal ADHD medication delivery system

Unlike treatments that are taken orally, the Daytrana patch efficiently delivers medicine through the skin and into the bloodstream, bypassing the digestive tract. Because Daytrana is not processed through the stomach, you can apply the patch when your child's stomach is full or before they have eaten, without affecting the absorption of medicine. The patch is designed to release medication continuously until it is removed, at the recommended 9-hour maximum wear-time or earlier. The level of medication in the bloodstream smoothly rises when the patch is applied and gradually descends when the patch is removed.

You should apply the patch 2 hours before an effect is needed. To help with symptom management during the morning routine, you may consider applying the patch while your child is still sleeping. The effects of the medication will continue for up to 3 hours after being removed.

Daytrana® (methylphenidate transdermal system) provides long-lasting symptom control for up to 10 hours when worn for 9 hours—the recommended maximum wear-time. When applied, Daytrana takes effect after 2 hours. Effects will last for up to 3 hours after being removed. Consult your doctor about early removal of the patch.

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Watch "How Daytrana works" to learn more about how the patch is different from other ADHD treatments.

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Talking to your doctor about Daytrana

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Use of the DAYTRANA® Patch

The Daytrana patch contains a prescription central nervous system (brain) stimulant medicine used to treat ADHD in children and adolescents 6 to 17 years old. Use of the Daytrana patch may help increase attention and decrease impulsive and hyperactive behavior. The Daytrana patch should be used as a part of a total treatment program for ADHD that may include counseling or other therapies.

Important Safety Information

IMPORTANT:
Daytrana is a controlled substance (CII) because it can be abused or lead to dependence. Keep Daytrana in a safe place to protect it from theft. Selling or giving away Daytrana may harm others and is against the law. Tell the prescribing doctor if your child has ever abused or been dependent on alcohol, prescription medicines or street drugs.

The Daytrana patch should not be used if your child has been diagnosed as very anxious, tense, or agitated; has an eye problem called glaucoma; has tics (repeated movements or sounds that cannot be controlled); has a diagnosis or family history of Tourette's syndrome; is taking a monoamine oxidase inhibitor (MAOI) medicine or has discontinued an MAOI medicine in the last 2 weeks; or is allergic to methylphenidate, acrylic adhesive, or silicone adhesive.

Serious heart problems have been reported with the Daytrana patch or other stimulant medicines including:

Tell the doctor if your child or a family member has any heart problems, heart defects, or increased blood pressure and heart rate. Remove the Daytrana patch and call the doctor right away if your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while using Daytrana. Before you start using Daytrana, tell your doctor if you have circulation problems in fingers or toes. Tell your doctor if you have or your child has numbness, pain, skin color change, or sensitivity to temperature in your fingers or toes. Call your doctor right away if you have or your child has any signs of unexplained wounds appearing on fingers or toes while taking Daytrana.

Serious mental (psychiatric) problems have been reported with the Daytrana patch or other stimulant medicines including:

Tell the doctor about any mental problems your child or family members have experienced including suicide or depression, bipolar illness, mania, or psychosis. Call the doctor right away if your child has any new or worsening mental symptoms or problems while using the Daytrana patch.

Be sure to tell the doctor if your child is pregnant or breast feeding.

Serious side effects such as seizures (this usually happens in children with a history of seizures), painful and prolonged erections (priapism), slowing of growth (weight and height), and eyesight changes or blurred vision have been reported with the Daytrana patch. Because of the potential for lasting damage, seek medical help immediately if you or your child develops priapism. Your child should have their height, weight, and blood work checked while using the Daytrana patch and the doctor may stop treatment if a problem is found during these check-ups. Allergic skin rash may occur. Stop using the Daytrana patch and see the doctor right away if swelling, bumps, or blisters happen at or around the site where the patch is applied. If the patch is worn longer than 9 hours in a day, or if more than 1 patch is worn at a time, too much medicine has been applied. Avoid exposing the Daytrana patch to direct external heat sources such as hair dryers, heating pads, electric blankets, heated water beds, or other heat sources while wearing the patch. Heating the patch could cause too much medicine to pass into your child's body and cause serious side effects.

The most common side effects seen while using the Daytrana patch include skin problems (redness, small bumps, itching) where the patch is applied, poor appetite, nausea, vomiting, stomach pain, weight loss, tics, trouble sleeping, mood swings, and dizziness.

Please read Medication Guide and Full Prescribing Information including the Boxed Warning regarding abuse and dependence.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.