Patch Application
Applying and removing the Daytrana patch is a quick and easy process. The tips below may help patients get the most from treatment with Daytrana.
Application2
- The patch should be applied to clean, dry skin on the hip area, below the waistline — alternate hips daily and apply at a new site if possible
- The patch should be applied 2 hours before an effect is desired
- Holding the patch so that the word Daytrana appears backwards, the patch should be gently bent along the score line
- Half the liner should be slowly removed and the patch pressed to the skin — exposed adhesive should not be touched. If you do, wash your hands immediately
- Holding the patch down, the rest of liner should be slowly removed and the exposed half pressed against the skin
- The patch should be pressed down with the palm of the hand for 30 seconds
Removal/disposal2
Upon removal, the patch should be folded in half, with sticky sides together, and discarded immediately in toilet or lidded container.
The patch should not be reused
Please note2:
Avoid applying external heat sources, such as heat pads, electric blankets, hair dryers, etc., to Daytrana.
Do not store Daytrana in the refrigerator or freezer.
For more detailed instructions for your patients on how to apply and remove the patch, click here.
Important Safety Information
Daytrana should not be used in patients with allergy to methylphenidate or patch components; marked anxiety, tension and agitation; glaucoma; tics, diagnosis or a family history of Tourette's syndrome; seizures; or during or within 14 days after treatment with monoamine oxidase inhibitors (MAOIs).
Sudden death has been reported in association with CNS stimulant treatment at usual doses in children and adolescents with structural cardiac abnormalities or other serious heart problems. Sudden deaths, stroke, and myocardial infarction have been reported in adults taking stimulant drugs at usual doses in ADHD. Physicians should take a careful patient history, including family history, and physical exam to assess the presence of cardiac disease. Patients who report symptoms of cardiac disease such as exertional chest pain and unexplained syncope should be promptly evaluated. Use with caution in patients whose underlying medical condition might be affected by increases in blood pressure or heart rate.
New psychosis, mania, aggression, growth suppression, and visual disturbances have been associated with the use of stimulants. Use with caution in patients with a history of: psychosis; EEG abnormalities; bipolar disorder; depression. Growth and hematologic monitoring is advised during prolonged treatment. Patients should avoid applying external heat to the Daytrana patch. Erythema has been commonly reported. Contact sensitization may occur.
Daytrana should be given cautiously to patients with a history of drug dependence and alcoholism. Chronic abuse can lead to marked tolerance and psychological dependence. Frank psychotic episodes can occur, especially with parenteral abuse. Careful supervision is required during withdrawal from abusive use, since severe depression may occur. Withdrawal following chronic therapeutic use may unmask symptoms of the underlying disorder.
Common adverse events reported by patients who received Daytrana in clinical trials were decreased appetite, insomnia, nausea, vomiting, decreased weight, tics, affect lability, and anorexia, consistent with adverse events commonly associated with the use of methylphenidate.
©2008 Shire US Inc., Wayne, PA 19087-5367, (800) 828-2088. All rights reserved.
Daytrana® is a registered trademark of Shire Pharmaceuticals Ireland Limited.
DAY-00032 08/08
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