Daytrana® skin care tips

Manage skin irritation with Daytrana skin care tips.

Because the Daytrana patch is applied to the skin, you and your child may notice mild skin redness or itching. This is common when using Daytrana, and in most cases skin irritation disappears within 24 hours. To get the most benefit when using the Daytrana patch, follow the ABCs of managing skin irritation below.

Alternate where you apply the patch

To minimize potential skin side effects, use Daytrana as prescribed and remember to alternate which hip you apply the patch to each day. Try not to use the same application site on either hip for several days.

Alternate where you apply the Daytrana patch to minimize skin irritation.

Be gentle

Always remove the patch gently from your child’s skin. If needed, use an oil-based product such as petroleum jelly or olive oil to remove patch adhesive residue from skin. Mild soaps are also recommended.

Clean, dry, apply

Before you apply a new Daytrana patch, your child’s skin must be clean and dry, with NO powder, oil, lotion, cuts, or irritation. Do not wash with soap or apply creams or lotions immediately before applying the patch. Redness is common and may not be a reason to stop treatment. Redness does not mean a rash.

NOTE: It is possible to develop an allergic reaction to Daytrana. Be sure to tell your child's doctor about any skin rash that develops in areas where Daytrana has been applied. Your child's doctor can determine if the rash is irritation or an allergic skin rash. If redness is accompanied by a more intense skin reaction that does not significantly improve within 48 hours or spreads beyond the patch site, discontinue use and contact your physician. Patients allergic to Daytrana may not be able to take methylphenidate in any form.

Loss of skin color (chemical leukoderma). Daytrana may cause a persistent loss of skin-color where the patch is applied or around the patch application site. Loss of skin-color, in some cases, has been reported at locations on the skin far from any application site. The loss of your skin-color may be permanent even after removing the patch or stopping use of Daytrana. Call your doctor immediately if you have changes in your skin-color.

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Frequently asked questions

Q: What happens if I accidentally put the Daytrana patch on the same hip two days in a row?

A: Placing the Daytrana patch on the same hip for two days in a row may increase the occurrence of skin irritation where the patch was applied. Read more.

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Use of the DAYTRANA® (methylphenidate transdermal system) Patch

The Daytrana patch contains a prescription central nervous system (brain) stimulant medicine used to treat ADHD in children and adolescents 6 to 17 years old. Use of the Daytrana patch may help increase attention and decrease impulsive and hyperactive behavior. The Daytrana patch should be used as a part of a total treatment program for ADHD that may include counseling or other therapies.

Important Safety Information

Daytrana is a controlled substance (CII) because it can be abused or lead to dependence. Keep Daytrana in a safe place to protect it from theft. Selling or giving away Daytrana may harm others and is against the law. Tell the prescribing doctor if your child has ever abused or been dependent on alcohol, prescription medicines or street drugs.

The Daytrana patch should not be used if your child has been diagnosed as very anxious, tense, or agitated; has an eye problem called glaucoma; has tics (repeated movements or sounds that cannot be controlled); has a diagnosis or family history of Tourette's syndrome; is taking a monoamine oxidase inhibitor (MAOI) medicine or has discontinued an MAOI medicine in the last 2 weeks; or is allergic to methylphenidate, acrylic adhesive, or silicone adhesive.

Serious heart problems have been reported with the Daytrana patch or other stimulant medicines including:

Tell the doctor if your child or a family member has any heart problems, heart defects, or increased blood pressure and heart rate. Remove the Daytrana patch and call the doctor right away if your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while using Daytrana. Before you start using Daytrana, tell your doctor if you have circulation problems in fingers or toes. Tell your doctor if you have or your child has numbness, pain, skin color change, or sensitivity to temperature in your fingers or toes. Call your doctor right away if you have or your child has any signs of unexplained wounds appearing on fingers or toes while using Daytrana.

Serious mental (psychiatric) problems have been reported with the Daytrana patch or other stimulant medicines including:

Tell the doctor about any mental problems your child or family members have experienced including suicide or depression, bipolar illness, mania, or psychosis. Call the doctor right away if your child has any new or worsening mental symptoms or problems while using the Daytrana patch. Tell your doctor if you, your child, or a family member has a history of vitiligo.

Be sure to tell the doctor if your child is pregnant or breast feeding.

Serious side effects such as seizures (this usually happens in children with a history of seizures), painful and prolonged erections (priapism), slowing of growth (weight and height), persistent loss of skin color (chemical leukoderma) and eyesight changes or blurred vision have been reported with the Daytrana patch. Because of the potential for lasting damage, seek medical help immediately if you or your child develops priapism. Your child should have their height, weight, and blood work checked while using the Daytrana patch and the doctor may stop treatment if a problem is found during these check-ups. Allergic skin rash may occur. Stop using the Daytrana patch and see the doctor right away if swelling, bumps, or blisters happen at or around the site where the patch is applied. If the patch is worn longer than 9 hours in a day, or if more than 1 patch is worn at a time, too much medicine has been applied. Avoid exposing the Daytrana patch to direct external heat sources such as hair dryers, heating pads, electric blankets, heated water beds, or other heat sources while wearing the patch. Heating the patch could cause too much medicine to pass into your child's body and cause serious side effects.

The most common side effects seen while using the Daytrana patch include skin problems (redness, small bumps, itching) where the patch is applied, poor appetite, nausea, vomiting, stomach pain, weight loss, tics, trouble sleeping, mood swings, and dizziness.

Please read Medication Guide and Full Prescribing Information including the Boxed Warning regarding abuse and dependence.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.